Brain Drug Targeting: The Future of Brain Drug Development by William M. Pardridge

By William M. Pardridge

The thesis of this cutting edge and hard e-book, first released in 2001, is that mind drug improvement has been limited through the failure of sufficient mind drug concentrating on, and that this is often an more and more pressing challenge as advancements in genomics bring about new generations of healing macromolecules. the writer, an international chief within the examine of the blood-brain barrier and its scientific implications, experiences the sector of neurotherapeutics from the perspective of drug concentrating on. He surveys the clinical and scientific foundation of drug supply throughout organic membranes, together with issues reminiscent of genetically engineered trojan horses for drug focusing on, antisense neurotherapeutics, and gene remedy of mind issues. At a time while there are few major new medicines in prospect for universal neurological ailments, this authoritative evaluation will inspire quite a lot of clinicians and neuroscientists to reexamine the improvement and use of substances in treating problems of the crucial apprehensive system.

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