Biochemistry of Platelets by David Phillips

By David Phillips

Biochemistry of Platelets is a finished evaluation of the biochemistry of platelets, with emphasis at the molecular foundation for a number of the organic techniques during which they take part. issues variety from stimulus-response coupling mechanisms to platelet contractile proteins, platelet membrane glycoproteins, and garage organelles in platelets and megakaryocytes. The expression and serve as of adhesive proteins at the platelet floor can also be discussed.

Comprised of 12 chapters, this e-book starts with an outline of the morphological and metabolic responses to agonists, in addition to the involvement of definite tactics within the coupling of agonist-receptor interactions to platelet responses. the next bankruptcy bargains with platelet arachidonate metabolism and platelet-activating issue, targeting the discharge of arachidonate from platelet lipid shops; pathways of platelet arachidonate metabolism and results of arachidonate metabolites; and inhibition of platelet arachidonate metabolism by means of aspirin. The constitution, functionality, and amendment in illness of platelet membrane glycoproteins are then mentioned, besides prothrombin activation on platelets and platelet rules of thrombus formation. Secreted platelet proteins as markers for pathological issues also are considered.

This monograph is meant as a reference for investigators all in favour of platelet learn in addition to a resource of data for these operating in different parts of organic investigation.

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